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小泉　英明

日立製作所　名誉フェロー

小泉　英明

理学博士

プロフィール

1971年東京大学教養学部基礎科学科卒業、同年日立製作所計測器事業部入社。1976年東京大学に論文を提出し理学博士。2000年 基礎研究所所長、2003年 技師長、2004年 フェローを経て 2017年より現職。

「心と脳の科学」という新たなtransdisciplinary分野を提起し、道を拓いた研究者として世界中に知られ、偏光ゼーマン原子吸光法の創出・実用化による環境計測をはじめに、f-MRI・光トポグラフィーによる脳機能計測技術を通じて脳科学から新・人間学など新しい学術分野の発展に寄与。

東京大学先端科学技術研究センター フェロー・ボードメンバー、公益社団法人日本工学アカデミー(EAJ)上級副会長・国際委員長、国際理工学アカデミー連合(CAETS)理事、中国工程院外国籍院士・東南大学栄誉教授、米国・欧州・豪州などの各種研究機関や財団のボードを兼務（B.D.）。

東京大学客員教授・北海道大学教授（客員部門）・第55代日本分析化学会会長・内閣府日本学術会議（SCJ）連携会員や省庁の多くの審議会・有識者会議で構成員・主査など歴任。環境・医療などの分野で、多くの新原理を創出して社会実装した。大河内賞計3回、米国R&D100賞計２回受賞（Oscars of Innovation、IR100賞含む）他。近著に『アインシュタインの逆オメガ: 脳の進化から教育を考える（Evolutionary Pedagogy）』（パピルス賞受賞作品、文藝春秋社刊）。

関連リンク

研究分野

  • 脳機能計測
  • 脳科学と人文学の融合
    （脳科学と教育、脳科学と倫理、脳科学と経済など）
  • 環境計測

主な文献（テーマ別）

偏光ゼーマン原子吸光法（PZAA）

  1. Koizumi, H. and Yasuda, K. (1974). A new method of atomic absorption spectrophotometry using the Zeeman effect." J Spectrosc Soc Japan, 23, 290-298.
  2. Koizumi, H. and Yasuda, K. (1975). "New Zeeman method for atomic spectro-photometry." Analytical Chemistry, 47(9), 1679-1682.
  3. Fukuzawa, T., Ebara, N., Katayama, M. and Koizumi, H. (1975). "The mechanism of amine sensitization of the emission of tris (dibenzoylmethano) europium (III)." Bulletin of the Chemical Society of Japan, 48(12), 3460-3463.
  4. Koizumi, H. and Yasuda, K. (1976). "A novel method for atomic absorption spectroscopy based on the analyte-Zeeman effect." Spectrochimica Acta Part B: Atomic Spectroscopy, 31(10), 523-535.
  5. Koizumi, H. and Yasuda, K. (1976). "An application of the Zeeman effect to atomic absorption spectrometry: a new method for background correction." Atomic Spectroscopy, 31(5), 237-255.
  6. Koizumi, H. and Yasuda, K., (1976). "Determination of lead, cadmium and zinc using the Zeeman effect in atomic absorption spectrometry." Analytical Chemistry, 48(8), 1178-1182.
  7. Koizumi, H., Yasuda, K. and Katayama, M. (1977). "Atomic absorption spectrophotometry based on polarization characteristic of the Zeeman effect." Analytical Chemistry, 49(8), 1106.
  8. Koizumi, H. and Katayama, M. (1977). "Line crossing observation in 2537 a line from mercury lamp." Physics Letters A, 63(3), 233-234.
  9. Koizumi, H. and Katayama M. (1977). "Observation of crossing effect in emission spectra from a copper lamp." Physics Letters A, 64(3), 285-286.
    (Also introduced in RESEARCH NEWS by Maugh, T.H. 2nd (1977). "The Zeeman Effect : A Unique Approach to Atomic Absorption." Science (New York, NY), 198 (4312), 39-41.)
  10. Koizumi, H. (1978). "Correction of spectral overlap interference by Zeeman atomic absorption spectrometry." Analytical Chemistry, 50(8), 1101-1105.
  11. Koizumi, H., Hadeishi, T. and McLaughlin, R.D. (1978). "Speciation of organometallic compounds by Zeeman atomic absorption spectrometry with liquid chromatography." Analytical Chemistry, 50(12), 1700-1701.
  12. Koizumi, H., McLaughlin, R.D. and Hadeishi, T. (1979). "High gas temperature furnace for species determination of organo-metallic compounds with HPLC-ZAA system." Analytical Chemistry, 51(3), 387-392.
  13. Koizumi, H., Hadeishi, T. and McLaughlin, R.D. (1979). "A new technique for the determination of isotopic species by using Zeeman scanning of an atomic line." Applied Physics Letters, 34 (4), 277-279.
  14. Koizumi, H., Hadeishi, T. and McLaughlin, R.D. (1979). "Detection of small molecules by magnetically tuned frequency modulated atomic line sources." Applied Physics Letters, 34 (6), 382-384.
  15. Koizumi, H., Hadeishi, T. and McLaughlin, R.D. (1980). "Nitric oxide determination by Zeeman- tuned frequency-modulated atomic line source." Analytical Chemistry, 52(3), 500-504.
  16. Koizumi, H., Hadeishi, T. and McLaughlin, R.D. (1981). "A new technique for the determination of SO2 by a Zeeman shifted atomic line." Spectrochimica Acta, 36, 483-485.
  17. Koizumi, H., Yamada, H., Yasuda, K., Uchino, K., and Oishi, K. (1981). "Polarized Zeeman effect atomic absorption spectrophotometry using a flame atomizer." Spectrochimica Acta Part B: Atomic Spectroscopy 36(7), 603-614.
  18. Koizumi, H., Oishi, K. and Yasuda, K. (1982), "Inverse Zeeman scanning for the measurement of emission line profile in far ultraviolet region." Applied Physics Letters, 40(2), 122-123.
  19. Koizumi, H., Sawakabu, H. and Koga, M. (1982). "Correction for double valued calibration curves in Zeeman effect atomic absorption spectrometry." Analytical Chemistry, 54(7), 1029-1032.
  20. Hadeishi, T., Koizumi, H., McLaughlin, R.D. and Millaud, J.E. (1982), "Tunable atomic line molecular (TALMS) spectrometer." Spectrochimica Acta Part B: Atomic Spectroscopy, 37(6), 501-509.
  21. Scott, D.R., Koizumi, H., Hadeishi, T. and McLaughlin, R.D. (1982). "High-resolution study of the rR (K."=3) structure of the 3390-A formaldehyde band." J Mol Spectrosc, 92, 272-275 (1982).
  22. Koizumi, H. (1994). "Analytical science as a new paradigm of analytical chemistry." J Seizon and Life Sci, 5, 393-407.

Magnetic Resonance Imaging (MRI) Equipment

  1. Sano, K., Yokoyama, T., Sato, S. and Koizumi, H. (1988). "A method of analytic phase correction in magnetic resonance imaging and its application to blood flow imaging, systems and computers in Japan." Systems and Computers in Japan, 19, 74-84 (1988) (The original Japanese version was published in 1986).
  2. Sano, K., Suzuki, K., Yokoyama, T. and Koizumi, H. (1987). "Image reconstruction from half of data using a phase map." 6th SMRM, 809.
  3. Sano, K., Yokoyama, T., Koizumi, H., Miki, H., Fukui, K. and Sadamoto, K. (1987). "Flow enhanced MR imaging by ECG trigger optimization." Radiology, 165(P), 92.
  4. Sano, K., Suzuki, K., Yokoyama, T. and Koizumi, H. (1987). "A technique of reducing fast-scan imaging time." Radiology, 165(P), 1100.
  5. Sano, K., Yokoyama, T., Suzuki, K., Koizumi, H., Miki, H., Takeda, S. and Sadamoto, K. (1988). "Enhanced rephrasing technique for MR Angiography." Radiology, 169(P), SPACE 910.
  6. Koizumi, H., Takeda, R., Takane, A., Miyamaoto, Y., Sano, K., Yokoyama, T., Miki, H. and Sadamoto, K. (1989). "High definition angiography using 0.5 T novel MRI system." in The First International Workshop on Magnetic Resonance Angiography, L'Aquila, Italy.
  7. Sano, K., Yokoyama, T. and Koizumi, H. (1989). "A gast 3-D reconstruction technique." 8th SMRM, 1170.
  8. Sano, K., Hayakawa K, Yokoyama, T., Koizumi, H., Miki, H., Takeda, S. and Sadamoto, K., (1989). "Improved three-dimensional MR angiography at 0.5 T." Radiology, 173(P), SPACE 518.
  9. Miki, H., Niida, A., Sadamoto, K., Hamamoto, K., Sano, K. and Koizumi, H. (1990). "0.5 Tesla three-dimensional MR angiography of cerebral aneurysms." 9th SMRM, 709.
  10. Miki, H., Niida, A., Sadamoto, K., Hamamoto, K., Sano, K., Yokoyama, T. and Koizumi, H. (1990). "0.5-T three-dimensional MR angiography of cerebral aneurysms." Radiology, 177(P), SPACE 267.
  11. Takane, A., Tsuda, M. and Koizumi, H. (1991). "Simultaneous bright and black three-dimensional angiography with steady-state free precession imaging." Radiology, 181(P), SPACE 900.
  12. Koizumi, H. (1991). "From Zeeman Atomic Absorption to Magnetic Resonance Imaging - An approach towards analytical science." Analytical Sciences, 7, 565-570.
  13. Sano, K., Yokoyama, T., Koizumi, H., Miki, H., Takeda, S. and Sadamoto, K. (1990). "3-dimensional MR angiography using a new rendering technique." 9th SMRM, 500.
  14. Zang, L.H., Wilbrink, J., Fielden, J., Takane, A. and Koizumi, H., "Correction of translational motion artifacts in multi-slice spin echo imaging using self-calibration." 10th SMRM, 1230 (1991).
  15. Wilbrink, J., Zang, L.H., Fielden, J., Takane, A. and Koizumi, H., "Motion correction by self-calibration for fast spin echo." 11th SMRM, 481 (1992).
  16. Wilbrink, J., Zang, L.H., Fielden, J., Takane, A. and Koizumi, H. (1992). "Automated motion artifact reduction with partial-Fourier image reconstruction." 11th SMRM, 664.
  17. Zang, L.H., Wilbrink, J., Fielden, J., Takane, A. and Koizumi, H. (1992). "Motion detection in magnetic resonance angiography." 11th SMRM, 2805.
  18. Zang, L.H., Wilbrink, J., Fielden, J., Takane, A. and Koizumi, H. (1992). "In-plane correction for multi-slice spin echo imaging by self-calibration and post-processing." 11th SMRM, 4239.
  19. Sano, K., Kato, C., Koizumi, H., Koyama, S. and Nishimura, H. (1992). "Fast spin echo imaging using blipped phase encoding." 11th SMRM, 4502.
  20. Wilbrink, J., Zang, L.H., Fielden, J., Takane, A. and Koizumi, H. (1992). "Motion correction in MR imaging by self-calibration." Radiology, 181(P), SPACE 10-040.
  21. Takane, A. and Koizumi, H. (1992). "MR imaging of brain surface using steady-state free precession." Mgn. Reson. Med., 25, 344-348.
  22. Takane, A., Tsuda, M., Koizumi, H., Koyama, S. and Yoshida, T. (1993). "Simultaneous imaging of MR angiography image and brain surface image with steady state free precession." Radiology, 189(P), SPACE 584PH.
  23. Zang, L.H., Wilbrink, J., Fielden, J., Takane, A. and Koizumi, H. (1993). "Correction of translation motion artifacts in multi-slice spin echo- imaging using self-calibration." Magn. Reson. Med., 29, 327-334.

機能的磁気共鳴画像法（f-MRI）

  1. Takahashi, T., Takiguchi, K., Itagaki, H., Onodera, Y., Yamamoto, E., and Koizumi, H. (1993). "Real time imaging of brain activation during imagination of finger tasks." 12th SMRM, 1415.
  2. Sekihara, K., Takeuchi, F., Kuriki, S. and Koizumi, H. (1994). "Reduction of brain noise influence in evoked neuromagnetic source localization using noise spatial correction." Phys. Med. Biol., 39, 937-946.
  3. Yamamoto, E., Onodera, Y., Itagaki, H., Sakai, K., Watanabe, E., Koizumi, H. and Miyashita, Y. (1994). "Determination of topographic maps of human somatosensory cortex with echo-planar MR imaging." Radiology, 100 years progress, SPACE 818NR.
  4. Watanabe, E., Sakai, K., Onodera, Y., Itagaki, H., Yamamoto, E., Mayanagi, Y. and Koizumi, H. (1995). "Functional MRI and its usage in neurosurgical navigation." J Comput Aided Surg, 1, 60-63.
  5. Sakai, K., Watanabe, E., Onodera, Y., Itagaki, H., Yamamoto, E., Koizumi, H. and Miyashita, Y. (1995). "Functional mapping of the human somatosensory cortex with echo-planar MRI." Magn Reson Med, 33, 736-743.
  6. Sakai, K., Watanabe, E., Onodera, Y., Uchida, I., Kato, H., Yamamoto, E., Koizumi, H. and Miyashita, Y. (1995). "Functional mapping of the human colour centre with echo-planar magnetic resonance imaging." Proc R Soc Lond B, 261, 89-98.
  7. Koizumi, H., Yamamoto, E., Sekihara, K., Sakairi, M., Kawaguchi, F. and Yokoyama, T. (1995). "Higher-order brain function analysis from the viewpoint of methodology." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (Koizumi, H., Ed.), 13-18, Hitachi, Ltd., Tokyo.
  8. Onodera, Y., Itagaki, H., Sakai, K., Watanabe, E., Miyashita, Y., Yamamoto, E. and Koizumi, H., (1995). "Somatotopical mapping of the human somatosensory cortex with ultra-fast MRI." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (Koizumi, H., Ed.), 52-53, Hitachi, Ltd., Tokyo.
  9. Konishi, S., Yoneyama, R., Itagaki, H., Uchida, I., Nakajima, K., Kato, H., Okajima, K., Koizumi, H. and Miyashita, Y. (1996). "Transient brain activity used in magnetic resonance imaging to detect functional areas." Neuroreport, 8, 19-23.
  10. Sekihara, K. and Koizumi, H. (1996). "Detecting cortical activities from fMRI time-course data using the MUSIC algorithm with forward and backward covariance averaging." J Magn Reson Med, 35, 807-813.

質量分析

  1. Hirabayashi, A., Sakairi, M. and Koizumi, H. (1994). "Sonic spray ionization method for atmospheric pressure ionization mass spectrometry." Anal. Chem., 66, 4557-4559.
  2. Hirabayashi, A., Sakairi, M. and Koizumi, H. (1995). "Sonic spray mass spectrometry." Anal.Chem., 67, 2878-2882.
  3. Takada, Y., Yoshida, M., Sakairi, M. and Koizumi, H. (1995). "Detection of γ-Aminobutyric Acid in a living rat brain using in vivo microdialysis-capillary electrophoresis/mass spectrometry." Rapid Commun. Mass Spectrom., 9, 895-896.
  4. Takada, Y., Sakairi, M. and Koizumi, H. (1995). "Atmospheric pressure chemical ionization interface for capillary electrophoresis/mass spectrometry." Anal. Chem., 67, 1474-1476.
  5. Takada, Y., Sakairi, M. and Koizumi, H. (1995). "On-line combination of micellar electrokinetic chromatography and mass spectrometry using an electrospray-chemical ionization interface." Rapid Commun. Mass Spectrom., 9, 488-490.
  6. Ozaki, H., Itou, N., Terabe, S., Takada, Y., Sakairi, M. and Koizumi, H. (1995). "Micellar electrokinetic chromatography-mass spectrometry using a high-molecular-mass surfactant on-line coupling with an electrospray ionization interface." J. Chromatogr., A716, 69-79.
  7. Hirabayashi, A., Sakairi, M., Takada, Y. and Koizumi, H., (1996). "Recent Progress in Atmospheric Pressure Ionization Mass Spectrometry." Trends in Anal. Chem., 16, 45-52.
  8. Hirabayashi, Y., Hirabayashi, A., Sakairi, M. and Koizumi, H. (1996). "Multiply-charged ion formation by sonic spray." Rapid Commun. Mass Spectrom., 10, 1703-1705.
  9. Hirabayashi, Y., Takada, Y., Hirabayashi, A., Sakairi, M. and Koizumi, H. (1996). "Direct coupling of semi-micro liquid chromatography and sonic spray ionization mass spectrometry for pesticide analysis." Rapid Commun. Mass Spectrom., 10, 1891-1893.

近赤外分光法（光トポグラフィ）

  1. Maki, A., Yamashita, Y., Ito, Y., Watanabe, E., Mayanagi, Y. and Koizumi, H. (1995). "Spatial and temporal analysis of human motor activity using noninvasive NIR topography." Med Phys, 22, 1997-2005.
  2. Yamashita, Y., Maki, A., Ito, Y., Watanabe, E., Mayanagi, Y., and Koizumi, H. (1995). Noninvasive near-infrared topography of the motor cortex activity." The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (Koizumi H, ed.), 54-55, Hitachi, Ltd., Tokyo.
  3. Maki, A., Yamashita, Y., Ito, Y., Watanabe, E., Mayanagi, Y., and Koizumi, H. (1995). "Spatial and temporal analysis of human motor activity using noninvasive NIR topography." Med Phys, 22, 1997-2005.
  4. Yamashita, Y., Maki, A. and Koizumi, H. (1996). "Near-infra-red topographic measurement system: Imaging of absorbers localized in a scattering medium." Rev Sci Instrum, 67, 730-732.
  5. Yamashita, Y., Maki, A., Ito, Y., Watanabe, E., Mayanagi, Y. and Koizumi, H. (1996). "Noninvasive near-infrared topography of human brain activity using intensity modulation spectroscopy." Opt Eng, 35, 1046-1049.
  6. Watanabe, E., Yamashita, Y., Maki, A., Ito, Y., and Koizumi, H. (1996). "Non-invasive functional mapping with multi-channel near-infrared spectroscopic topography in humans." Neurosci Lett, 205, 41-44.
  7. Maki, A., Yamashita, Y., Watanabe, E. and Koizumi, H. (1996). "Visualizing human motor activity by using non-invasive optical topography." Front Med Biol Eng, 7, 285-297.
  8. Maki, A. and Koizumi, H. (1996). "Reconstructing absorber images in a three-dimensional scattering medium by using photon-path data." in OSA Topics on Advances in Optical Imaging and Photon Migration Vol.II (Alfano, R.R. and Fujimoto, J.G., eds.), 299-304.
  9. Yamashita, Y., Maki, A., and Koizumi, H. (1996). "A noninvasive optical topography measurement system." in OSA Topics on Advances in Optical Imaging and Photon Migration Vol.II (Alfano, R.R. and Fujimoto, J.G., eds.), 344-347.
  10. Maki, A., Yamashita, Y., Ito, Y., Watanabe, E. and Koizumi, H. (1996). "Spatial and Temporal Analysis of Human Motor Activity Using Noninvasive Optical Topography." in OSA Topics on Advances in Optical Photon Migration, 2, 357-362.
  11. Shinohara, Y., Haida, M., Shinohara, N., Kawaguchi, F., Ito, Y. and Koizumi, H.(1997). "Towards near-infrared imaging of the brain." in Optical Imaging of Brain Function and Metabolism II (Villringer, A. and Dirnagl, U., eds.) , 85-89, Plenum Press, New York.
  12. Kogure, K., Yamashita, Y., Maki, A., Itagaki, H., Izumiyama, M. and Koizumi, H. (1997). "Functional near-infrared spectrography (fNIR) in the neurology ward, J. Cereb. Blood Flow Metab. 17(1), 555.
  13. Koizumi, H., Ochiai, T., Okahashi, T., Yamashita, Y., Maki, A., Yamamoto, T., Inagami, Y., Yoshizawa, H., Iwata, M., Omori, T. and Yasunaga, M. ((1998). "Dynamic optical topography and the real-time PDP chip: An analytical and synthetical approach to higher-order brain functions." Proceedings of 5th International Conference on Neural Information Processing, 337-340.
  14. Watanabe, E., Maki, A., Kawaguchi, F., Takashiro, K., Yamashita, Y., Koizumi, H. and Mayanagi, Y. (1998). "Non-invasive assessment of language dominance with near-infrared spectroscopic mapping." Neurosci Lett, 256, 49-52.
  15. Watanabe, E., Maki, A., Kawaguchi, F., Takashiro K, Yamashita, Y., Koizumi, H. and Mayanagi, Y. (1998). "Non-invasive cerebral blood volume measurement during seizures using multi-channel near infrared spectroscopic topography." J Epilepsy, 11, 335-340.
  16. Shiotsuka, S., Atsumi, Y., Ogata, S., Yamamoto, R., Igawa, M., Takahashi, K., Hirasawa, H., Koyama, K., Maki, A., Yamashita, Y., Koizumi, H., and Toru, M. (1998). "Cerebral blood volume in the sleep measured by near-infrared spectroscopy." Psychiatry Clin. Neurosci. 52(2), 172-173.
  17. Koizumi, H., Yamashita, Y., Maki, A., Yamamoto, T., Ito, Y., Itagaki, H. and Kennan, R. (1999). "Higher-order brain function analysis by trans-cranial dynamic NIRS imaging." Journal of Biomedical Optics, 4(4), 403-413.
  18. Yamamoto, T., Yamashita, Y., Yoshizawa, H., Maki, A., Iwata, M., Watanabe, E. and Koizumi, H. (1999). "Noninvasive measurement of language function by using optical topography." In Proceedings of SPIE, the International Society for Optical Engineering, 3597, 230-237, Society of Photo-Optical Instrumentation Engineers.
  19. Koizumi, H. (2000). "From the Editor." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 215-216, Hitachi, Ltd., Tokyo.
  20. Yamashita, Y., Maki, A. and Koizumi, H. (2000). "Dynamic optical topography." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 61-64, Hitachi, Ltd., Tokyo.
  21. Yamamoto, T., Tanikawa Y, Maki, A., Yamashita, Y., Kennan R, Yamada Y, and Koizumi, H. (2000). "Location accuracy of topographic images." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 69-72, Hitachi, Ltd., Tokyo.
  22. Yamamoto Y, Kennan R, Maki, A., Yamashita, Y., Ochi H, Yamamoto, T., and Koizumi, H. (2000). "Simultaneous cerebral mapping sensorimotor activation by using functional magnetic resonance imaging and near-infrared optical topography, "In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 73-75, Hitachi, Ltd., Tokyo.
  23. Ito, Y., Kennan R, Watanabe, E. and Koizumi, H. (2000). "Assessment of heating effects in skin by irradiation of near-infrared laser light." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 76-79, Hitachi, Ltd., Tokyo.
  24. Watanabe, E., Maki, A., Kawaguchi, F., Yamashita, Y., and Koizumi, H. (2000). "Clinical applications of NIRS functional mapping in neurosurgery." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 91-94, Hitachi, Ltd., Tokyo.
  25. Haida, M., Shinohara, Y., Ito, Y., Yamamoto, T., Kawaguchi, F., and Koizumi, H. (2000). Brain function of an ALS patient in complete locked-in state, In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 95-97, Hitachi, Ltd., Tokyo.
  26. Takahashi, K., Ogata, S., Atsumi, Y., Tagaya, H., Yamashita, Y., Maki, A., Yamamoto, T., Koizumi, H., Shiotsuka, S., Igawa, M., Koyama, K., Hirasawa, H. and Yamamoto, R. (2000). "From the editor." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 101-102, Hitachi, Ltd., Tokyo.
  27. Shiotsuka, S., Igawa, M., Koyama, K., Hirasawa, H., Takahashi, K., Ogata, S., Atsumi, Y., Tagaya, H., Yamashita, Y., Maki, A., Yamamoto, T., Koizumi, H. and Yamamoto, R. (2000). "Activation level in visual cortex changed contingent on the frequency of pattern shift measured by 24 channel NIRSI." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., (Ed.)), 103-104, Hitachi, Ltd., Tokyo.
  28. Izumiyama, M., Kogure, K., Kogure, T., Maki, A., Itagaki, H., Yamashita, Y., Yamamoto, T. and Koizumi, H. (2000). "NIR cinematography on speech and atypical development of the cortical function." in The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 105-112, Hitachi, Ltd., Tokyo.
  29. Iwata, N.K., Ugawa, Y., Watanabe, E., Yamashita, Y., Koizumi, H. and Kanazawa, I. (2000). "Inter-hemispheric connection between bilateral hand motor areas studied with near-infrared spectroscopic mapping and transcranial magnetic stimulation." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 113-115, Hitachi, Ltd., Tokyo.
  30. Maki, A., Dehaene-Lambertz, G., Pena, M., Fujiwara, M., Mehler, J., and Koizumi, H. (2000). "Hemodynamic fluctuation in the neonate brain evaluated using optical topography." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 116-117, Hitachi, Ltd., Tokyo.
  31. Konishi, Y., Taga, G., Takaya, R., Maki, A., Tachibana, T. and Koizumi, H. (2000). "Two month revolution." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 118-121, Hitachi, Ltd., Tokyo.
  32. Yoshizawa, H., Yamashita, Y., Yamamoto, T., Maki, A., Koizumi, H., Watanabe, E. and Iwata, M. (2000). "Non-invasive imaging of language function by optical topography." In The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 131-133, Hitachi, Ltd., Tokyo.
  33. Kennan, R., Yamashita, Y., Maki, A., Ito, Y., Yamamoto, T. and Koizumi, H. (2000). "Frequency response of auditory stimulus monitored by optical topography." in The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 138-140, Hitachi, Ltd., Tokyo.
  34. Kato, T., Yamashita, Y., Maki, A., Yamamoto, T., Ichikawa, N. and Koizumi, H. (2000). "Temporal dissociation of phonological loop after language spoken." in The Trans-disciplinary Symposium on the Frontier of Mind-Brain Science and Its Practical Applications (II) (Koizumi, H., Ed.), 145-148, Hitachi, Ltd., Tokyo.
  35. Ito, Y., Kennan, R.P., Watanabe, E. and Koizumi, H. (2000). "Assessment of heating effects in skin during continuous wave near infrared Spectroscopy." J Biomed Opt, 5, 383-390.
  36. Taga, G., Konishi, Y., Maki, A., Tachibana, T., Fujiwara, M. and Koizumi, H. (2000). "Spontaneous oscillation of oxy- and deoxy- hemoglobin changes with a phase difference throughout the occipital cortex of newborn infants observed using non-invasive optical topography." Neurosci Lett, 282, 101-104.
  37. Takahashi, K., Ogata, S., Atsumi, Y., Yamamoto, R., Shiotsuka, S., Maki, A., Yamashita, Y., Yamamoto, T., Koizumi, H., Hirasawa, H. and Igawa, M. (2000). "Activation of the visual cortex imaged by 24-channel near-infrared spectroscopy." J Biomed Opt 5, 93-96.
  38. Watanabe, E., Maki, A., Kawaguchi, F., Yamashita, Y., Koizumi, H. and Mayanagi, Y. (2000). "Noninvasive cerebral blood volume measurement during seizures using multichannel near infrared spectroscopic topography." J Biomed Opt , 5, 287-290.
  39. Maki, A., Pena, M., Dehaene-Lambertz, G., Kawaguchi, F., Fujiwara, M., Ichikawa, N., Koizumi, H. and Mehler, J. (2000). "Measurement of infant language function by using optical topography." Nou-no-kagaku, 22.
  40. Kato, H., Izumiyama, M., Shiga, Y., Saito, N., Koizumi, H., Takahashi, A. and Itoyama, Y. (2001). "Hand motor cortical area reorganization following cerebral infarction evaluated with functional MRI, near infrared spectroscopic imaging, and trans-cranial magnetic stimulation." No To Shinkei, 53, 869-874 (in Japanese).
  41. Kogure K, Izumiyama, M., Kogure, T., Maki, A., Itagaki H, Yamamoto Y, Yamamoto, T. and Koizumi, H. (2001). "Functional plasticity of the brain after ischemic injury assessed by near infrared topography." in Maturation Phenomenon in Cerebral Ischemia IV (Bazan, N.G. et al., eds.) pp.103-110, Springer-Verlag, Berlin.
  42. Igawa, M., Atsumi, Y., Takahashi, K., Shiotsuka, S., Hirasawa, H., Yamamoto, R., Maki, A., Yamashita, Y. and Koizumi, H. (2001). "Activation of visual cortex in REM sleep measured by 24-channel NIRS imaging." Psychiatry Clin. Neurosci. 55(3), 187-188.
  43. Yamamoto, T., Maki, A., Yamashita, Y., Tanikawa Y, Yamada Y, Koizumi, H. (2001). "Noninvasive brain function measurement system: optical topography." Proc SPIE Int Soc Opt Eng, 4250, 339-350.
  44. Yamashita, Y., Maki, A. and Koizumi, H. (2001). "Wavelength dependence of the precision of noninvasive optical measurement of oxy-, deoxy-, and total-hemoglobin concentration." Med Phys, 28, 1108-1114.
  45. Kato, H., Izumiyama, M., Koizumi, H., Takahashi, A. and Itoyama, Y. (2002). "Near-infrared spectroscopic topography as a tool to monitor motor reorganization after hemispheric stroke: a comparison with functional MRI." Stroke, 33, 2032-2036.
  46. Yamamoto, T., Maki, A., Kadoya, T., Tanikawa, Y., Yamada, Y., Okada, E. and Koizumi, H. (2002). "Arranging optical fibers for the spatial resolution improvement of topographical images." Phys Med Biol, 47, 3429-3440.
  47. Kennan, R.P., Kim, D., Maki, A., Koizumi, H. and Constable, R.T. (2002). "Non-invasive assessment of language lateralization by transcranial near infrared optical topography and functional MRI." Hum Brain Mapp, 16, 183-189.
  48. Kennan, R.P., Horovitz, S.G., Maki, A., Yamashita, Y., Koizumi, H. and Gore, J.C. (2002). "Simultaneous recording of event-related auditory oddball response using transcranial near infrared optical topography and surface EEG." Neuroimage, 16, 587-592.
  49. Koizumi, H., Yamamoto, T., Maki, A., Yamashita, Y., Sato, H., Kawaguchi, H. and Ichikawa, N., "Optical topography: practical problems and new applications." Appl Opt, 42, 3054-3062 (2003).
  50. Obata, A., Morimoto, K., Sato, H., Maki, A. and Koizumi, H. (2003). "Acute effects of alcohol on hemodynamic changes during visual stimulation assessed using 24-channel near-infrared spectroscopy." Psychiatry Res, 123(2), 145-152.
  51. Pena, M, Maki, A., Kovacic, D., Dehaene-Lambertz, G., Koizumi, H., Bouquet, F. and Mehler, J. (2003). "Sounds and silence: an optical topography study of language recognition at birth." Proc Natl Acad Sci USA, 100(20), 11702-11705.
  52. Taga, G., Asakawa, K., Maki, A., Konishi, Y., Koizumi, H. (2003). Brain imaging in awake infants by near-infrared optical topography, Proc Natl Acad Sci, 100 (19), 10722-10727.
  53. Yamamoto, T., Okada, E., Kawaguchi, F., Maki, A., Yamada, Y. and Koizumi, H. (2003). "Optical fiber arrangement of optical topography for spatial resolution improvement" in Biomedical Optics 2003, 487-496, International Society for Optics and Photonics.
  54. Koizumi, H. (2004). "The concept of ‘developing the brain': a new natural science for learning and education." Brain Development, 26(7), 434-441.
  55. Tsujimoto, S., Yamamoto, T., Kawaguchi, H., Koizumi, H., and Sawaguchi, T. (2004). "Prefrontal cortical activation associated with working memory in adults and preschool children: an event-related optical topography study." Cereb Cortex, 14, 703-712.
  56. Koizumi, H., Maki, A., Yamamoto, T., Sato, H., Yamamoto, Y. and Kawaguchi, H. (2005). "Non-invasive brain-function imaging by optical topography." TrAC Trends in Analytical Chemistry, 24(2), 147-156.
  57. Obata, A., Morimoto, K., Sato, H., Takeshita, T., Kawaguchi, H., Koizumi, H. and Maki, A. (2005). "Effects of alcohol on hemodynamic and cardiovascular reaction in different genotypes." Psychiatry Res, 139, 65-72.
  58. Sato, H., Fuchino, Y., Kiguchi, M., Katura, T., Maki, A., Yoro, T. and Koizumi, H. (2005). "Intersubject variability of near-infrared spectroscopy signals during sensorimotor cortex activation." J Biomed Opt 10, 44001.
  59. Fuchino, Y., Sato, H., Maki, A., Yamamoto, Y., Katura, T., Obata, A., Koizumi, H. and Yoro, T. (2006). "Effect of fMRI acoustic noise on sensorimotor activation examined using optical topography." Neuroimage, 32, 771-777.
  60. Sato, H., Kiguchi, M., Maki, A., Fuchino, Y., Obata, A., Yoro, T. and Koizumi, H. (2006). "Within-subject reproducibility of near-infrared spectroscopy signals in sensorimotor activation after 6 months." J Biomed Opt 11, 014021 (2006).
  61. Kiguchi, M., Ichikawa, N., Atsumori, H., Kawaguchi, F., Sato, H., Maki, A. and Koizumi, H. (2007). "Comparison of light intensity on the brain surface due to laser exposure during Optical topography and solar irradiation." Journal of biomedical optics, 12 (6), 062108-062108.
  62. Koizumi, H. (2007). "Present and the future of brain imaging in Mind, Brain and Education." in Application of Brain-function imaging to the realm of education (Koizumi, H., Ed.), Inaugural Conference of International Mind, Brain and Education Society.
  63. Utsugi, K., Obata, A., Sato, H., Katura, T., Sagara, K., Maki., A., Koizumi, H. (2007). "Development of an optical brain-machine interface." Conf Proc IEEE Eng Med Biol Soc, 5338-41.
  64. Suda, M., Morimoto, K., Obata, A., Koizumi, H., Maki, A. (2008). "Emotional responses to music: towards scientific perspectives on music therapy." Neuroreport, 19(1), 75-8.
  65. Suda, M., Morimoto, K., Obata, A., Koizumi, H., Maki, A. (2008). "Cortical responses to Mozart's sonata enhance spatial-reasoning ability." Neurol Res, 30 (9), 885-8.
  66. Atsumori, H., Kiguchi, M., Katura, T., Funane, T., Obata, A., Sato, H. Manaka, T., Iwamoto, M., Maki, A., Koizumi, H. and Kubota, K. (2010). ""Noninvasive imaging of prefrontal activation during attention-demanding tasks performed while walking using a wearable optical topography system."" Journal of biomedical optics 15(4), 046002-046008
  67. Aoki, R., Funane, T. and Koizumi, H. (2010). "Brain Science of Ethics: Present Status and the Future." Journal of Mind, Brain, and Education, 4(4), 188-195.
  68. Sato, H., Aoki, R., Katura, T., Matsuda, R., Koizumi, H. (2011). "Correlation of within-individual fluctuation of depressed mood with prefrontal cortex activity during verbal sorking memory task: optical topography study." Journal of Biomedical Optics, 16(12), 126007.
  69. Aoki, R., Katsura, T., Utsugi, K., Koizumi, H., Matsuda, R., and Maki, A. (2011). "Relationship of negative mood with prefrontal cortex activity during working memory tasks: an optical topography study." Neuroscience Research,70(2), 189-96.
  70. Sato, H., Obata, A.N., Moda, I., Ozaki, K., Yasuhara, T., Yamamoto, Y., Kiguchi, M., Maki, A., Kubota, K. and Koizumi, H. (2011). "Application of near-infrared spectroscopy to measurement of hymodynamic signals accompanying stimulated salaiva secretion." J Biomed Opt, 16(4), 047002.
  71. Funane, T., Kiguchi, M., Atsumori, H., Sato, H., Kubota, K. and Koizumi, H. (2011). "Synchronous activity of two people's prefrontal cortices during a cooperative task measured by simultaneous near-infrared spectroscopy." Journal of Biomedical Optics, 16 (7), 077011-077011.

編書

2014年
アインシュタインの逆オメガ（文藝春秋）
2011年
脳科学の真贋（日刊工業新聞社）
2011年
脳の科学史（角川書店）
2010年
赤ちゃんのための脳科学（かもがわ出版）
2008年
脳科学と芸術：恋う・癒す・究める（工作舎）
2005年
脳は出会いで育つ「脳科学と教育入門」（青灯社）
2000年
脳図鑑21：育つ・学ぶ・癒す（工作舎）
2000年
The Frontier of Mind-Brain Science and Its Practical Applications (II). Tokyo: Hitachi, Ltd.
1998年
環境計測の最先端（三田出版）
1995年
The Frontier of Mind-Brain Science and Its Practical Applications. Tokyo: Hitachi, Ltd.

共著/編集

  1. Kawashima, R. & Koizumi, H. (Eds.) (2003). "Learning Therapy." Sendai, Japan: Tohoku University Press.

その他、セクション・章の貢献

  1. Koizumi, H. (1995). "Encyclopedia of Analytical Science." London: Academic Press Co.
  2. Koizumi, H. (2007). "A New Science of Humanity: A trial for the integration of Natural Sciences and the Humanities towards Human Security and Well-being." In M.S. Sorondo, (Ed.), What is our real knowledge about human being?, Vatican: Pontifical Academy of Sciences.
  3. Koizumi, H. (2008) "Developing the brain: A functional imaging approach to learning and educational sciences." In A.M. Battro, K.W. Fischer, P. Lena (Eds.), Educated Brain, Cambridge: Cambridge University Press.
  4. Koizumi, H. (2010) "Towards a new education philosophy." In M. Suarez-Orozco & C. Bajaj (Eds.), Educating the whole child in the whole world, New York, NY: New York University Press.
  5. Koizumi, H. (2012). "Brain-Science and Education in Japan." In S. Della Sala & M. Anderson (Eds.), Neuroscience in Education, Oxford: Oxford University Press.

主な表彰

2013年2月
日本化学会賞（日本化学会）
2012年12月
中国工程院 外国籍 院士
2012年3月
日本分析化学会名誉会員
2010年
日本分光学会学会賞
2009年4月
日本工学アカデミー会員
2008年4月
日本学術会議連携会員
2010年11月
日本分光学会学会賞
2008年3月
日本化学会 フェロー
2004年4月
日経BP技術賞大賞
2004年3月
第50回 大河内記念
2002年10月
R&D 100賞(米国) Award: The Optical Topography® System, ETG-100 [R&D Magazine]
2000年3月
第46回 大河内記念技術賞
1983年6月
全国発明表彰・科学技術庁長官賞
1977年10月
IR-100賞(米国)
1977年3月
第23回大河内記念技術賞
1976年4月
研究功績者・科学技術庁長官賞

学位

1976年10月
理学博士「ゼーマン効果を用いた原子吸光分析法」（東京大学）

略歴

1971年6月
東京大学教養学部基礎科学科卒業
1971年7月
日製産業株式会社入社
1973年9月
株式会社日立製作所転入
1979年9月
同社　那珂工場　光学装置設計部　技師
1983年2月
同社　那珂工場　光学装置設計部　主任技師
1992年8月
同社　中央研究所　主管研究員
1999年8月
同社　基礎研究所長
2001年4月
同社　中央研究所　主管研究長
2003年4月
同社　基礎研究所　主管研究長
2003年10月
同社　研究開発本部　技師長
2004年3月
同社　フェロー
2017年4月
同社　名誉フェロー
(～現在に至る)

その他の経歴

2001年
内閣府原子力委員会　専門委員
2001年
科学技術振興機構「脳科学と教育」研究プログラム研究総括（2007年まで）
2003年
山崎貞一賞選考委員会　委員
2003年
財団法人ソニー教育財団　理事・幼児教育支援プログラム審査委員長
2004年
科学技術振興機構「脳科学と社会」研究開発領域の領域総括（2010年まで）
2005年
財団法人生存科学研究所　理事
2005年
科学技術振興機構　研究領域「脳の機能発達と学習メカニズムの解明」領域アドバイザー（2011年まで）
2007年
国立大学法人東京大学先端科学技術研究センター　客員教授（2009年まで）
2008年
国立大学法人東京大学大学院 総合文化研究科・教養学部運営諮問会議　委員
2008年
文部科学省「子どもの徳育に関する懇談会」委員（2010年まで）
2008年
国立大学法人山形大学グローバルCOE研究拠点　board委員
2008年
くもん学習療法センター学習療法研究会　理事（2010年まで）
2009年
財団法人倉田記念日立科学技術財団　評議員
2009年
国立大学法人東京大学先端科学技術研究センター　ボードメンバー
2010年
国立大学法人東京農工大学経営協議会　委員
2012年
中国工程院　外国籍院士
2014年
公益社団法人日本工学アカデミー　副会長、理事

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